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USE OF CYCLOHEXANEHEXOL DERIVATIVES IN THE TREATMENT OF OCULAR DISEASES
专利权人:
WARATAH PHARMACEUTICALS INC.
发明人:
JoAnne McLAURIN,Antonio CRUZ
申请号:
US14157122
公开号:
US20140135403A1
申请日:
2014.01.16
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to methods of treating ocular diseases in a subject by administering to the subject a therapeutically effective amount of one or more cyclohexanehexyl derivatives, or salts thereof, or a medicament comprising a cyclohexanehexol derivative and a pharmaceutically acceptable carrier. More specifically, the invention provides a medicament comprising at least one cyclohexanehexyl derivative of formula (III) or (IV) useful in preventing or treating ocular diseases, by modulating the folding, oligomerization or aggregation of amyloid β in ocular cells. Methods of administration of these medicaments include systemic, transpleural, oral, intravenously, intraarterial, intramuscular, topical, via inhalation, transdermal, subcutaneous, intraperitoneal, gastrointestinal, and directly to the eye or tissues surrounding the eyes. Formulae (III), (IV).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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