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Use of cyclohexanehexol derivatives in the treatment of ocular diseases
专利权人:
Waratah Pharmaceuticals Inc.
发明人:
Cruz, Antonio
申请号:
AU2008238577
公开号:
AU2008238577B2
申请日:
2008.04.11
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention relates to methods of treating ocular diseases in a subjectby administering to the subject a therapeutically effective amount of one ormore cyclohexanehexol derivatives, or salts thereof, or a medicament comprisinga cyclohexanehexol derivative and a pharmaceutically acceptable carrier.More specifically, the invention provides a medicament comprising at leastone cyclohexanehexol derivative of formula (III) or (IV) useful in preventingor treating ocular diseases, by modulating the folding, oligomerization oraggregation of amyloid β in ocular cells. Methods of administration ofthese medicaments include systemic, transpleural, oral, intravenously, intraarterial,intramuscular, topical, via inhalation, transdermal, subcutaneous, intraperitoneal,gastrointestinal, and directly to the eye or tissues surrounding the eyes. Formulae(III), (IV).
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中国工程科技知识中心
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