Milan N. Stojanovic,Renjun Pei,Steven Michael Forna Taylor
申请号：
US13245201
公开号：
US09243024B2
申请日:
2011.09.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Disclosed are aptamer/drug conjugate complexes and the use of such complexes, together with a trigger compound, to inducibly release a drug. Also disclosed are methods for establishing a drug reservoir in a subject using these complexes, whereby drug may be released as needed. One example of such a complex is an aptamer/insulin conjugate complex from which insulin may be released by an innocuous, orally administrable trigger, such as quinine.
