An instrument set (1) and a surgical instrument. The instrument set (1) includes an overturning platform assembly, two sets of driving wires, two wire rotating bodies (12, 18), and four output wires. Each set of driving wires includes two driving wires, two fixed points formed by each set of driving wires on an inner rotating member (114) are symmetrical about a first intersection point, four fixed points formed by four driving wires on the inner rotating member (114) are sequentially connected to form a first parallelogram, the intersection point of diagonal lines of the first parallelogram is the first intersection point, the other end of each of the two driving wires in each set of driving wires is wound on the corresponding wire rotating body (12, 18) in the opposite direction, and therefore the overturning platform assembly is driven to move by the four driving wires, and then motion of the overturning platform assembly is transferred to an end instrument assembly (3) through the output wires, so that multi-direction and multi-degree-of-freedom motion of the end instrument assembly (3) is achieved, thereby simplifying the design of the instrument set (1), reducing the volume of the instrument set (1), and increasing the space utilization of the instrument set (1).