Simona M. Ceccarelli;Gerald Lewis Kaplan;Mirjana Andjelkovic;Odile Chomienne;Jefferson Wright Tilley;Patrizio Mattei
发明人:
Mirjana Andjelkovic,Simona M. Ceccarelli,Odile Chomienne,Gerald Lewis Kaplan,Patrizio Mattei,Jefferson Wright Tilley
申请号：
US12430934
公开号：
US08344027B2
申请日:
2009.04.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention relates to novel 4-dimethylaminobutyric acid derivatives of the formulawherein A1, A2, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments in methods for the treatment of diseases modulated by CPT2 inhibitors.
