Simona M. Ceccarelli;Mirjana Andjelkovic;Odile Chomienne;Patrizio Mattei
发明人:
Mirjana Andjelkovic,Simona M. Ceccarelli,Odile Chomienne,Patrizio Mattei
申请号:
US12430941
公开号:
US08349893B2
申请日:
2009.04.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This invention relates to novel 4-trimethylammoniobutyrates of the formulawherein A1, R1, m and n are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds inhibit carnitine palmitoyl transferase (CPT) activity, in particular CPT2 activity, and can be used as medicaments.