INC.;H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE
发明人:
PARK, Jong,SELLERS, Thomas,POW-SANG, Julio M.,LIN, Hui-Yi
申请号：
USUS2013/040337
公开号：
WO2013/170020A2
申请日:
2013.05.09
申请国别(地区):
US
年份:
2013
代理人:
摘要：
In particular, disclosed is a method for treating a patient with prostate cancer that involves genotyping a nucleic acid sample from the subject for one or more single nucleotide polymorphism (SNP) alleles in one or more genes angiogenesis, comparing the one or more SNP alleles to control allele frequencies to produce a SNP signature, and analyzing the SNP signature to generate a risk score. The risk score can represent the likelihood that the patient's prostate cancer will recur following radical prostatectomy. In particular embodiments, a high risk score in a patient with positive margins is an indication of a high risk of prostate cancer recurrence.
