The Role of Peroxisome Proliferator-Activated Receptor gamma in Immune Responses to Enteroaggregative Escherichia coli Infection

负责人：

ImmPort

关键词：

Wild-type and T cell-specific PPARg null C57BL\/6 mice were fed protein-deficient diets (2% protein) at weaning. After three days on diet mice were challenged with 5x10^9 cfu EAEC strain JM221 by orogastric gavage. Mice were monitored daily for weight and disease activity until the designated project endpoint.

DOI：

doi:10.21430/m36i96jiiz

摘要：

. Methods/Principal Findings: Wild-type and T cell-specific PPARg null C57BL/6 mice were fed protein-deficient diets at weaning and challenged with 5x10^9 cfu

Data from: Cellular hypertrophy and increased susceptibility to spontaneous calcium-release of rat left atrial myocytes due to elevated afterload

负责人：

关键词：

spontaneous calcium release;atrial myocytes;hypertrophy;pressure overload remodelling;calcium transients

DOI：

doi:10.5061/dryad.70gk2

摘要：

center were much smaller. Western blotting showed a decreased L-type Ca channel expression but no significant changes in RyR or RyR phosphorylation

Data from: Influence of factors of cryopreservation and hypothermic storage on survival and functional parameters of multipotent stromal cell

负责人：

关键词：

Multipotent Stromal Cells;Placenta;Cryopreservation

DOI：

doi:10.5061/dryad.mk556

摘要：

for this type of cells. This study demonstrates perspectives for creation of new defined cryopreservation methods towards GMP standards.

Data from: Virus resistance is not costly in a marine alga evolving under multiple environmental stressors

负责人：

关键词：

Phycodnavirus;environmental change;Ostreococcus;trade-off;Marine Viral Ecology;Cost of resistance;Prasinovirus;Ostreococcus tauri;Evolution;Virus-Host Interactions

DOI：

doi:10.5061/dryad.vr3hk

摘要：

for evolutionary costs of maintaining antiviral resistance, we examined whether O. tauri populations composed of each resistance type differed in thei

Data from: Elovanoids counteract oligomeric ?-Amyloid-induced gene expression and protect photoreceptors

负责人：

关键词：

DOI：

doi:10.5061/dryad.59zw3r233

摘要：

the RPE, we used primary human RPE cell cultures and demonstrated that OA? caused cell damage, while ELVs protected and restored gene expression as in mouse

Data from: Notch and Nodal control expression of a forkhead factor in the specification network of a multipotent progenitor population in sea urchin

负责人：

关键词：

Strongylocentrotus purpuratus;hedgehog;multipotency;Notch;coelomic pouch;left right asymmetry;FoxY

DOI：

doi:10.5061/dryad.np321

摘要：

in this cell type. Our experiments place foxY at the top of the regulatory hierarchy underlying specification of a cell type maintaining developmental potency.

Data from: Nrf2 ameliorates DDC-induced sclerosing cholangitis and biliary fibrosis and improves the regenerative capacity of the liver.

负责人：

Fragoulis, Athanassios

关键词：

cre validation supporting data/analyses

DOI：

doi:10.5061/dryad.d8vs845

摘要：

) was fed to Nrf2-KO mice (Nrf2-/-), mice with liver-specific hyper-activated Nrf2 (HKeap1-/-) and wild type (WT) littermates to induce cholangitis

Data from: Modelling of dysregulated glucagon secretion in type 2 diabetes by considering mitochondrial alterations in pancreatic alpha cells

负责人：

关键词：

biophysics;nonlinear dynamics;Biomedical engineering;complexity;biophysics;nonlinear dynamics;Biomedical engineering;complexity

DOI：

doi:10.5061/dryad.9n2k1vk

摘要：

Type 2 diabetes mellitus (T2DM) has been associated with insulin resistance and the failure of ?-cells to produce and secrete enough insulin

Colored chart showing the emergence of terminally differentiated cells in C. elegans<\/i> from 200 to 400 minutes of embryogenesis.