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Data from: Evolution of increased survival in RNA viruses specialized on cancer-derived cells
负责人:
关键词:
Ecology: evolutionary;virus;Trade offs;Evolution: virulence;Life history: trade offs;Ecology: microbial
DOI:
doi:10.5061/dryad.1ft93
摘要:
cell type. Our results shed new light on the causes and consequences of "sit and wait" infection strategies in RNA viruses.
Data from: Transcriptome dynamics of the stomatal lineage: birth, amplification, and termination of a self-renewing population
负责人:
关键词:
Arabidopsis thaliana;asymmetric cell division;stomata;bHLH transcription factor;FACS-isolation;single-cell type transcriptome
DOI:
doi:10.5061/dryad.5st3t
摘要:
to quantify gene expression from labeled cells isolated by fluorescence-activated cell sorting to generate cell-type-specific transcriptomes during development
Data from: Threshold effect of growth rate on population variability of Escherichia coli cell lengths
负责人:
关键词:
bacterial cell division;bacteria;population variability;cell-size;RecA;multifork replication
DOI:
doi:10.5061/dryad.2bs69
摘要:
s. We find cell length variability in the mutant to be greater than wild-type, a phenotype that is rescued by plasmid-based RecA expression. Additionally, we find tha
Data from: Gene expression profiles of alveolar type II cells of chronic obstructive pulmonary disease: a case-control study
负责人:
关键词:
cell biology;Chronic airways disease;Respiratory medicine (see Thoracic Medicine);human;alveolar type II epithelial cell;gene expression;Molecular Biology;COPD
DOI:
doi:10.5061/dryad.mc4s1
摘要:
Objectives: The aim of this study was to identify the gene expression pattern specific in alveolar epithelial type II cells (ATII cells) isolated
Data from: Sweepstake evolution revealed by population-genetic analysis of copy-number alterations in single genomes of breast cancer
负责人:
关键词:
molecular evolution;Single-cell sequencing;Coalescent Theory;bioinformatics;Cancer genomics;Copy-number alteration
DOI:
doi:10.5061/dryad.71jp0
摘要:
her developed to quantitatively analyse the single-cell sequencing data. We developed a bioinformatics framework that was combined with molecular
Development of targeted therapies for peroxisome biogenesis disorders
负责人:
关键词:
Molecular Biology peroxisome biogenesis disorders peroxins PEX1 high-content screening small molecules induced pluripotent stem cells HepG2 cells Pex1-p.G844D mouse
DOI:
doi:10.25549/usctheses-c40-298640
摘要:
t directly address the cell type specificity of disease and the nature of the mutations found in the patient population.
Data from: Rate of novel host invasion affects adaptability of evolving RNA virus lineages
负责人:
关键词:
Experimental evolution;epistasis;Contingency;Adaptation;alphavirus;Sindbis virus
DOI:
doi:10.5061/dryad.9b30b
摘要:
, we experimentally evolved 144 Sindbis virus lineages in replicated tissue-culture environments, which transitioned from being dominated by a permissive host cell type
Data from: Transcriptomic inspection revealed a possible pathway regulating the formation of the high-quality brush hair in Chinese Haimen goat
负责人:
关键词:
Brush Hair;differentially expressed genes;Heat stress;Goat
DOI:
doi:10.5061/dryad.12f01
摘要:
The high-quality brush hair, or Type III brush hair, is coarse hair but with a tip and little medulla, which uniquely grows in the cervical carina
Data from: Impaired hippocampal place cell dynamics in a mouse model of the 22q11.2 deletion
负责人:
Zaremba, Jeff
关键词:
hippocampus calcium imaging in vivo imaging two-photon imaging schizophrenia 22q11.2 deletion syndrome place cells place cell stability spatial learning reward learning
DOI:
doi:10.5061/dryad.rq560
摘要:
dynamics in health and disease remains elusive. Using chronic two-photon Ca2+ imaging in hippocampal area CA1 of wild-type and Df(16)A+/? mice, an animal model

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