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Data from: Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.44j0zpc9v
- 摘要：
- and pro-survival proteins, including CDK2 and CDK9, have entered clinical development. Here, we provide the first disclosure of the chemic
Data from: Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating
- 负责人：
- DOI：
- doi:10.5061/dryad.92pd3
- 摘要：
- for tissue. The assay success rate on 1,000 consecutive samples in clinical practice was 99.8%. Digital sequencing of plasma-derived DNA is indic
Study of isoniazid-resistant tuberculosis: mycobacterial genotypic characterization and clinical features in human subjects
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- 关键词：
- Clinical & Biomedical Investigations tuberculosis isoniazid virulence katG drug-resistance clinical presentation
- DOI：
- doi:10.25549/usctheses-m755
- 摘要：
- to determine if MTB-INHr genotype is associated with distinct clinical features. A retrospective case-control study design was used to compare
\u2022\tRegulatory requirement for drug development and approval in United States: review
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- 关键词：
- 111701 Aboriginal and Torres Strait Islander Health 111001 Aged Care Nursing 111702 Aged Health Care 110301 Anaesthesiology 110901 Autonomic Nervous System 111501 Basic Pharmacology Biomarkers 110601 Biomechanics 111201 Cancer Cell Biology 111202 Cancer Diagnosis
- DOI：
- doi:10.6084/m9.figshare.3381274.v1
- 摘要：
- involving drugdiscovery, laboratory development, animal studies, clinicaltrials, and regulatory registration. This lengthy process isnecessary to assure
Data from: Head-to-head drug comparisons in multiple sclerosis: urgent action needed
- 负责人：
- DOI：
- doi:10.5061/dryad.h5g7nt7
- 摘要：
- Disease-modifying drugs are changing the natural history of multiple sclerosis (MS). However, currently available clinical trial data ar
Data from: A quantitative electrophysiological biomarker of duplication 15q11.2-q13.1 syndrome
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- 关键词：
- Dup15q
- DOI：
- doi:10.5061/dryad.2th78
- 摘要：
- al (EEG) pattern characterized by excessive activity in the beta band has been noted in clinical reports. We asked whether EEG power in the beta band
Data from: Improving the recruitment activity of clinicians in randomised controlled trials - a systematic review
- 负责人：
- DOI：
- doi:10.5061/dryad.4dg4v0c8
- 摘要：
- ; patient-clinician relationship; effect on patients; effect on clinical practice; individual benefits for clinicians; and methods associated with successful
Data from: The complex relationship of exposure to new Plasmodium infections and incidence of clinical malaria in Papua New Guinea
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- DOI：
- doi:10.5061/dryad.f9154
- 摘要：
- and for exposure at individual level. Relationships between molFOB, parasite prevalence and clinical incidence were assessed in a treatment-to-reinfection cohort
Analysis and visualization of multi-mode optical spectral-signature bioimaging data for in vivo applications
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- 关键词：
- Biomedical Engineering multi-mode imaging spectral signature imaging hyperspectral imaging fluorescence lifetime imaging
- DOI：
- doi:10.25549/usctheses-m809
- 摘要：
- s and cell biology in clinical practice, our level of understanding at tissue and pre-clinical levels needs to be enhanced using novel imaging-based technologies
Additional file 1: of Comparison of virulence of Francisella tularensis ssp. holarctica genotypes B.12 and B.FTNF002-00
- 负责人：
- 关键词：
- Medicine Microbiology Genetics Immunology Mental Health Infectious Diseases Virology Computational Biology
- DOI：
- doi:10.6084/m9.figshare.c.3688216_d1
- 摘要：
- Weight data and clinical sign scores of Francisella tularensis ssp. holarctica infected Fischer 344 rats. The animals were infected with the B.12
