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Data from: Fitness change in relation to mutation number in spontaneous mutation accumulation lines of Chlamydomonas reinhardtii
负责人:
关键词:
Chlamydomonas reinhardtii;spontaneous mutations;mutational effects;mutation accumulation;Chlamydomonas
DOI:
doi:10.5061/dryad.4sg14
摘要:
Although all genetic variation ultimately stems from mutations, their properties are difficult to study directly. Here, we used multi
Data from: Fitness of Arabidopsis thaliana mutation accumulation lines whose spontaneous mutations are known
负责人:
关键词:
Genetic Variation;Arabidopsis thaliana;Mutations;present;quantitative genetics
DOI:
doi:10.5061/dryad.rk5fp6n9
摘要:
) to mutation effects on fitness implies spatial and/or temporal variation in selection on new mutations and could contribute to the maintenance
Data from: Temperature effects on life-history trade-offs, germline maintenance and mutation rate under simulated climate warming
负责人:
关键词:
Life history;environmental change;trade-off;Adaptation;mutation rate;Phenotypic Plasticity
DOI:
doi:10.5061/dryad.6dd04
摘要:
rate. Here we challenged experimental lines of seed beetle, evolved at ancestral temperature or under simulated climate warming, to repair induced mutations
Data from: Validation of targeted next-generation sequencing for RAS mutation detection in FFPE colorectal cancer tissues: comparison
负责人:
关键词:
Formalin-fixed paraffin-embedded;Colorectal cancer;Targeted next-generation sequencing;RAS mutations;Ion Torrent Personal Genome Machine
DOI:
doi:10.5061/dryad.3447g
摘要:
Objective: To validate the targeted next-generation sequencing (NGS) platform-Ion Torrent PGM for KRAS exon 2 and expanded RAS mutations detecti
Data from: Mutation accumulation and the formation of range limits
负责人:
关键词:
Range formation;Dispersal;mutation load;environmental gradients
DOI:
doi:10.5061/dryad.4tr2v
摘要:
r been overlooked in the context of range formation; the accumulation of mutation load. We find that mutation accumulation severely reduces the extent of a range ac
Data from: The basis of antagonistic pleiotropy in hfq mutations that have opposite effects on fitness at slow and fast growth rates
负责人:
关键词:
Fitness;Escherichia coli;bacterial evolution
DOI:
doi:10.5061/dryad.5bd50
摘要:
nct ways. In addition, these results point to a source of variation in experimental measurement of the selective advantage of a mutation; estimates of fitness nee
Data from: The distribution of mutational fitness effects of phage ?X174 on different hosts
负责人:
关键词:
Mutations;Escherichia coli;population genetics;Parasitism;Salmonella typhimurium;Adaptation;Fitness
DOI:
doi:10.5061/dryad.565r1
摘要:
Adaptation depends greatly on the distribution of mutation fitness effects (DMFE), but the phenotypic expression of mutations is often environment
Data from: Mutation rate evolution in partially selfing and partially asexual organisms
负责人:
关键词:
modifier model;clonality;Deleterious mutation;self-fertilization;multilocus population genetics
DOI:
doi:10.5061/dryad.1j6b0
摘要:
on caused by the mutations produced (that should generally favor lower mutation rates, given that most mutations affecting fitness are deleterious
Data from: Population persistence under high mutation rate: from evolutionary rescue to lethal mutagenesis
负责人:
关键词:
Distribution of extinction times;Fisher\u2019s Geometric Model;Lethal mutagenesis;Extinction dynamics;evolutionary rescue;fitness landscape
DOI:
doi:10.5061/dryad.n7c08t7
摘要:
the accumulation of multiple mutations in a single genome. Here, we extend this model to study the rescue process in an asexual population where the mutation
Data from: Genome dynamics of hybrid Saccharomyces cerevisiae during vegetative and meiotic divisions
负责人:
关键词:
hybrid yeast;mutation rate;loss of heterozygosity
DOI:
doi:10.5061/dryad.s14m0
摘要:
Mutation and recombination are the major sources of genetic diversity in all organisms. In the baker's yeast, all mutation rate estimates ar

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