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Data from: Unraveling the causes of adaptive benefits of synonymous mutations in TEM-1 ?-lactamase
负责人:
关键词:
TEM-1;Cefotaxime;epistasis;Escherichia coli;betalactamase;fitness landscape;resistance gene;synonymous mutations;bulk competition
DOI:
doi:10.5061/dryad.hp370m2
摘要:
of the combinations of mutations exceeded the resistance of the largest-effect mutation and there were synthetically neutral combinations. By cons
Data from: The phenotypic effects of spontaneous mutations in different environments
负责人:
关键词:
Ecology: evolutionary;Life history: evolution;Evolution: experimental;morphology;Phenotypic Plasticity;Daphnia;Mutation;Genetics: ecological
DOI:
doi:10.5061/dryad.mj5m8
摘要:
in their abilities to accrue mutational variation and how the environment influences expression of mutant phenotypes yields insight int
Data from: Effects of genotype on rates of substitution during experimental evolution
负责人:
关键词:
Escherichia coli;molecular evolution;epistasis;Selection - Experimental;variation
DOI:
doi:10.5061/dryad.36td2
摘要:
on size, mutation rates, or in the distribution of fitness effects (DFE) of available beneficial mutations. By whole genome sequencing of Escherichia coli populati
Data from: Epistasis buffers the fitness effects of rifampicin-resistance mutations in Pseudomonas aeruginosa
负责人:
关键词:
Mutations;Pseudomonas aeruginosa;epistasis
DOI:
doi:10.5061/dryad.8858
摘要:
Epistatic interactions between resistance mutations in antibiotic-free environments potentially play a crucial role in the spread of resista
Data from: Impact of deleterious mutations, sexually antagonistic selection and mode of recombination suppression on transitions bet
负责人:
关键词:
DOI:
doi:10.5061/dryad.5cc26s8
摘要:
Deleterious mutations accumulating on non-recombining Y chromosomes can drive XY to XY turnovers, as they allow to replace the old mutation-loaded
Data from: The mutational structure of metabolism in Caenorhabditis elegans
负责人:
关键词:
Caenorhabditis elegans;mutational bias;mutational variance;metabolome;mutation accumulation;Holocene;Fitness
DOI:
doi:10.5061/dryad.2dn09
摘要:
A properly functioning organism must maintain metabolic homeostasis. Deleterious mutations degrade organismal function, presumably at least in par
Data from: Spontaneous mutation accumulation in multiple strains of the green alga, Chlamydomonas reinhardtii
负责人:
关键词:
Mutations;population genetics;variation;Fitness
DOI:
doi:10.5061/dryad.s8330
摘要:
Estimates of mutational parameters, such as the average fitness effect of a new mutation and the rate at which new genetic variation for fitness
Data from: The mutational decay of male-male and hermaphrodite-hermaphrodite competitive fitness in the androdioecious nematode C. elegans
负责人:
关键词:
Caenorhabditis elegans;mutation accumulation;mutational variance;mutational bias;spontaneous mutation
DOI:
doi:10.5061/dryad.2ng4k
摘要:
Androdioecious Caenorhabditis have a high frequency of self-compatible hermaphrodites and a low frequency of males. The effects of mutations
Data from: Test of synergistic interactions among deleterious mutations in bacteria
负责人:
关键词:
epistasis;Fitness;Escherichia coli
DOI:
doi:10.5061/dryad.rg8mb
摘要:
of Escherichia coli carrying one, two or three successive mutations and measured their fitness relative to an unmutated competitor. The relationship between mutation
Data from: Benefit of transferred mutations is better predicted by the fitness of recipients than by their ecological or genetic relatedness
负责人:
关键词:
Beneficial mutations;Mutation-by-genetic background interactions;Escherichia coli;epistasis;Horizontal gene transfer
DOI:
doi:10.5061/dryad.t60n5
摘要:
c and ecological similarity of recipient strains relative to the donor strain in which the mutations were selected. By contrast, mutation effects were strongl

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