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Circadian and brain state modulation of network hyperexcitability in Alzheimer's disease - rodent datasets
- 负责人:
- University Of Edinburgh;;University Of Edinburgh
- DOI:
- doi:10.7488/ds/2319
- 摘要:
- amyloid precursor protein (APP) with mutations that cause familial AD, and compared a transgenic model that overexpresses human APP (J20), to a knock-in model expressing APP
Hepatitis B virus X protein regulation of β-catenin and NANOG and co-regulatory role with YAP1 in HCC malignancy
- 负责人:
- 关键词:
- Molecular Microbiology and Immunology hepatocellular carcinoma HCC hepatitis B virus X protein HBx NANOG YAP1 β-catenin tumor initiating cells TICs
- DOI:
- doi:10.25549/usctheses-c3-615884
- 摘要:
- titutively active β-catenin with NANOG promotes self-renewal ability and HBx protein plays a key role for oncogenic transformation of hepatic progenitor cells.
Data from: Low-dose proton radiation effects in a transgenic mouse model of Alzheimer's Disease - implications for space travel
- 负责人:
- Vlkolinsky, Roman
- 关键词:
- Mice Electrophysiology Animal behavior Protons Hippocampus Brain electrophysiology Alzheimer's disease Cytokines
- DOI:
- doi:10.5061/dryad.0008d
- 摘要:
- /PSEN1 transgenic (TG) and wild type (WT) mice with protons (150 MeV; 0.1-1.0 Gy; whole body) and evaluated functional and biochemical hallmarks of AD
Datasets from gender specific auditory brainstem responses (ABRs) from Cav2.3+\/+, Cav2.3+\/- and Cav2.3-\/- mice following click and tone burst
- 负责人:
- 关键词:
- Transgenic Animal Mouse Phenotyping Calcium Channels Animal Auditory System Auditory Evoked Response
- DOI:
- doi:10.17632/g6ygz2spzx
- 摘要:
- intained with random intra-strain mating obtaining all genotypes (Mouse Genome Informatics; MGI Ref. ID J: 66144). For subsequent ABR recordings, Cav2.3+/+ controls
Data from: Horizontal gene transfer of acetyltransferases, invertases and chorismate mutases from different bacteria to diverse recipients
- 负责人:
- Baum, Thomas
- 关键词:
- plant-parasitic nematodes horizontal gene transfer phylogenetics model selection analysis evolution
- DOI:
- doi:10.5061/dryad.pb68n
- 摘要:
- Background: Hoplolaimina plant-parasitic nematodes (PPN) are a lineage of animals with many documented cases of horizontal gene transfer (HGT
An mRNA expression atlas for the domestic chicken generated by the meta-analysis of RNA-seq datasets
- 负责人:
- University Of Edinburgh;;University Of Edinburgh
- DOI:
- doi:10.7488/ds/2137
- 摘要:
- 3 male and 3 female broilers (Ross 308), and 3 female layers (CSF1R-MacApple transgenic NOVOgen Brown), all 8 weeks of age. The dataset attached here contains
Data from: Sex allocation adjustment to mating group size in a simultaneous hermaphrodite
- 负责人:
- DOI:
- doi:10.5061/dryad.16vk4
- 摘要:
- ween mating group size and sex allocation, which we here achieve in the simultaneously hermaphroditic flatworm Macrostomum lignano. Using transgenic focal worms
Data from: Direct behavioral and neurophysiological evidence for retronasal olfaction in mice
- 负责人:
- DOI:
- doi:10.5061/dryad.3cs6v
- 摘要:
- ly imageable in humans- codes retronasal smell in anesthetized rat. The powerful awake transgenic mouse, however, would be a valuable additional model
Data from: Effects of pasture and forest microclimatic conditions on the foraging activity of leaf-cutting ants
- 负责人:
- DOI:
- doi:10.5061/dryad.2jm63xskh
- 摘要:
- The fragmentation and transformation of land cover modify the microclimate of ecosystems. These changes have the potential to modify
Data from: Bigger testes increase paternity in a simultaneous hermaphrodite, independently of the sperm competition level
- 负责人:
- Vellnow, Nikolas
- 关键词:
- sperm competition local sperm competition (LSC) simultaneous hermaphrodite sex allocation mating group size male fitness gain curve testis size paternity success
- DOI:
- doi:10.5061/dryad.fd407
- 摘要:
- in group sizes of either three (strong LSC) or eight individuals (weak LSC). Specifically, using transgenic focal individuals expressing a dominant