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Data from: Stability of spontaneous, correlated activity in mouse auditory cortex
- 负责人：
- DOI：
- doi:10.5061/dryad.85387h3
- 摘要：
- and how that organization is modulated by stimuli or altered in models of disease.
Data from: Independent reversals to terrestriality in squirrels (Rodentia: Sciuridae) support ecologically mediated modes of adaptation
- 负责人：
- 关键词：
- locomotion;Macroevolution;Sciuridae;Ancestral range estimation;continental colonization;speciation
- DOI：
- doi:10.5061/dryad.5646p
- 摘要：
- The family Sciuridae is one of the most widespread and ecologically diverse lineage of rodents and represents an ideal model for investigating
Data from: Predicting drug-induced liver injury using ensemble learning methods and molecular fingerprints
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.1k8m6p2
- 摘要：
- the hepatotoxicity of compounds during the early stages of drug trials. In this study, we developed an ensemble model using three machine learning algorithms and 12
Characterizing the Retinal Function of Psammomys obesus: A Diurnal Rodent Model to Study Human Retinal Function
- 负责人：
- 关键词：
- Neuroscience
- DOI：
- doi:10.6084/m9.figshare.3406606.v3
- 摘要：
- Purpose: To compare the retinal function of a diurnal murid rodent, Psammomys obesus, with that of Wistar albino rat and human subjects
Characterizing the Retinal Function of Psammomys obesus: A Diurnal Rodent Model to Study Human Retinal Function
- 负责人：
- 关键词：
- Neuroscience
- DOI：
- doi:10.6084/m9.figshare.3406606
- 摘要：
- Purpose: To compare the retinal function of a diurnal murid rodent, Psammomys obesus, with that of Wistar albino rat and human subjects
Data from: Multiple regression modelling for estimating endocranial volume in extinct Mammalia
- 负责人：
- DOI：
- doi:10.5061/dryad.38v59
- 摘要：
- . Model-predicted volume correlates strongly with measured volume (R2 = 0.993) and prediction error is between 16% and 19%. Error decreases if models
Data from: Phylogenetic ANOVA: the Expression Variance and Evolution model for quantitative trait evolution
- 负责人：
- 关键词：
- Ornstein-Uhlenbeck model;Plasticity;expression adaptation;population variance;comparative expression
- DOI：
- doi:10.5061/dryad.r122k
- 摘要：
- A number of methods have been developed for modeling the evolution of a quantitative trait on a phylogeny. These methods have received renewed int
) mouse model of Parkinson\u2019s disease and CAG\u2081\u2084\u2080 knock-in mouse model of Huntington's disease
- 负责人：
- DOI：
- doi:10.25549/usctheses-c40-270850
- 摘要：
- and putamen (striatum) in PD and its animal models and contributes to motor impairments. Striatal medium spiny neurons (MSNs) can be delineated int
Data from: Coadapted genomes and selection on hybrids: Fisher's geometric model explains a variety of empirical patterns
- 负责人：
- DOI：
- doi:10.5061/dryad.2hb2br7
- 摘要：
- ). The predictions are generally supported, and the model explains a number of surprising empirical patterns. Our approach enables novel and complementary use
Development of targeted therapies for peroxisome biogenesis disorders
- 负责人：
- 关键词：
- Molecular Biology peroxisome biogenesis disorders peroxins PEX1 high-content screening small molecules induced pluripotent stem cells HepG2 cells Pex1-p.G844D mouse
- DOI：
- doi:10.25549/usctheses-c40-298640
- 摘要：
- , and the new cellular and animal models can be the next generation screening tools to discover and characterize more active compounds. ? In addition, I describe
