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Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment
负责人:
关键词:
Adrenocortical carcinoma;immunotherapy;humanized mouse PDX model;anti-PD-1
DOI:
doi:10.5061/dryad.f8q4350
摘要:
Context: While the development of immune checkpoint inhibitors has transformed treatment strategies of several human malignancies, research models
Circadian and brain state modulation of network hyperexcitability in Alzheimer's disease - rodent datasets
负责人:
University Of Edinburgh;;University Of Edinburgh
关键词:
Alzheimer's disease EEG Epilepsy Medicine and Dentistry::Pre-clinical Medicine
DOI:
doi:10.7488/ds/2319
摘要:
Network hyperexcitability is a feature of Alzheimer's disease (AD) as well as numerous transgenic mouse models of AD. While hyperexcitability in AD
Data from: Opportunities and challenges of Integral Projection Models for modeling host-parasite dynamics
负责人:
关键词:
Integral Projection Model parasite demography infectious disease dynamics murine malaria measles
DOI:
doi:10.5061/dryad.07mc1
摘要:
of disease incidence. Mathematical models that integrate infection and demography are consequently a key tool for informing expectations for disease
Data from: Experimentally verified parameter sets for modelling heterogeneous neocortical pyramidal-cell populations
负责人:
关键词:
Wistar rat;pyramidal neurons;dynamic IV method;Neocortex;single neuron modelling;reduced neuron models
DOI:
doi:10.5061/dryad.d30k7
摘要:
Models of neocortical networks are increasingly including the diversity of excitatory and inhibitory neuronal classes. Significant variability
Data from: Weighing homoplasy against alternative scenarios with the help of macroevolutionary modeling: a case study on limb bones of fossorial
负责人:
关键词:
femur;Ornstein-Uhlenbeck model;locomotion;Sciuromorpha;Scapula;convergence;selective regime
DOI:
doi:10.5061/dryad.ng94td0
摘要:
was assessed via likelihood scoring of all considered models. The homoplasy hypothesis could never be confirmed as the single most likely model. Regardin
Data from: Mechanical factors direct mouse aortic remodeling during early maturation
负责人:
关键词:
mechanical modeling;arterial mechanics;Mus musculus;cardiovascular;elastin;extracellular matrix;fibulin-5
DOI:
doi:10.5061/dryad.v1q15
摘要:
mouse models of elastic fibre disease, such as those caused by the absence of fibulin-5 expression (Fbln5?/?). Adult Fbln5?/? mice have disorganized elastic
mouse model of Huntington's disease
负责人:
关键词:
DOI:
doi:10.5061/dryad.51110
摘要:
A variety of mouse models have been developed that express mutant huntingtin (mHTT) leading to aggregates and inclusions that model
Genetic review of mouse and human cleft lip and palate
负责人:
关键词:
Cranio-Facial Biology mouse cleft lip and palate human cleft lip and palate comparative anatomy
DOI:
doi:10.25549/usctheses-m2150
摘要:
the following: genetic disorders, chromosomal abnormalities, teratogenic exposures, sporadic, and unknown causes. The causes are being tested through animal model studies. Howeve
Data from: From the cover: three-dimensional (3d) heparg spheroid model with physiologically relevant xenobiotic metabolism competence and hepatocyte
负责人:
关键词:
DOI:
doi:10.5061/dryad.s05v3
摘要:
arch and drug development. While significant progress has been made to address this challenge using invitro liver models, these approaches often fail due to inadequate tissue
Data from: Regulation of reproductive processes with Dynamic Energy Budgets
负责人:
关键词:
DEB theory;Bioenergetics;Dynamic Energy Budget;rainbow trout;Oncorhynchus mykiss
DOI:
doi:10.5061/dryad.58j9r88
摘要:
and liver, egg diameter and plasma content of vitellogenin and estradiol in rainbow trout (Oncorynchus mykiss) by fitting these models to published

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