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Data from: Ageratina adenophora causes spleen toxicity by inducing oxidative stress and pyroptosis in mice
负责人:
Hu, Yanchun
关键词:
oxidative stress reactive oxygen species nod-like receptor protein 3 pyroptosis
DOI:
doi:10.5061/dryad.gf2np70
摘要:
a pivotal role in regulating animal or human health and disease. The object of this study was to determine the mechanism underlying splenic toxicity induced
Data from: Digestive capacity and toxicity cause mixed diets in red knots that maximize energy intake rate
负责人:
关键词:
Trade offs;bird;Foraging: ecology;Physiology: digestive;Foraging: behavior;Foraging: theory;Ecology: behavioral;wetlands
DOI:
doi:10.5061/dryad.5fp4g
摘要:
es to maximize energy intake. The model correctly predicted the preferences of the captive birds, which depended on the digestive quality and toxicity of thei
Cylindrospermopsin toxicity in mice following a 90-d oral exposure
负责人:
关键词:
Biochemistry Cell Biology Genetics Pharmacology 59999 Environmental Sciences not elsewhere classified 39999 Chemical Sciences not elsewhere classified Marine Biology 60506 Virology
DOI:
doi:10.6084/m9.figshare.6182216.v1
摘要:
. Toxicity included effects indicative of both hepatic and renal dysfunction. In humans, symptoms progressed from initial hepatomegaly, vomiting, and malaise
Data from: Myelin basic protein induces neuron-specific toxicity by directly damaging the neuronal plasma membrane
负责人:
关键词:
neurotoxicity;toxicity;Neurobiology;electrostatic interaction;myelin basic protein;membrane damage;cultured primary neurons;Neurotrauma
DOI:
doi:10.5061/dryad.211gr
摘要:
ally bound to the extracellular surface of the neuronal plasma membrane and induced neurotoxicity in vitro. This effect of MBP on neurons was basici
Data from: Identification of the additional mitochondrial liabilities of 2-hydroxyflutamide when compared to its parent compound, flutamide
负责人:
关键词:
DILI;Flutamide;2-hydroxyflutamide;Mitochondria
DOI:
doi:10.5061/dryad.jj456
摘要:
e has been limited investigation into the potential mitochondrial toxicity of 2-hydroxyflutamide and its contribution to flutamide-induced liver injury
Data from: Expression profiling of human pluripotent stem cell-derived cardiomyocytes exposed to doxorubicin—integration and visualization of multi
负责人:
关键词:
cardiomyocytes;toxicity;multi-omics data;proteomics;human pluripotent stem cells;doxorubicin
DOI:
doi:10.5061/dryad.g335f
摘要:
t the cardiotoxicity is dose-dependent and that there is a variation in time-to-onset of toxicity, and gender- and age differences suggests that several mechanisms ma
Data from: Using a multi-stage hESC model to characterize BDE-47 toxicity during neurogenesis
负责人:
Chen, Hao
关键词:
DOI:
doi:10.5061/dryad.2vp18qv
摘要:
the mechanism(s) underlying PBDE-toxicity, we conducted global transcriptomic and methylomic analyses of BDE-47. We identified 589 genes
Data from: Multi-behavioral endpoint testing of an 87-chemical compound library in freshwater planarians
负责人:
Zhang, Siqi
关键词:
DOI:
doi:10.5061/dryad.mk6m608
摘要:
our screening methodology to allow for fast screening of multiple behavioral endpoints, developmental toxicity, and mortality. Using an 87-compound library provided
Data from: Genome-scale characterization of toxicity-induced metabolic alterations in primary hepatocytes
负责人:
关键词:
DOI:
doi:10.5061/dryad.04vk390
摘要:
t biomarkers of liver toxicity using the Transcriptionally Inferred Metabolic Biomarker Response (TIMBR) algorithm. We profiled alterations in cellular

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