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Data from: Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates
- 负责人：
- DOI：
- doi:10.5061/dryad.p6261d6
- 摘要：
- r molecular target, addressing a key aspect of the mechanism of action of N-BPs that may have significant clinical relevance.
Data from: Differential temperature sensitivity of synaptic and firing processes in a neural mass model of epileptic discharges explains
- 负责人：
- DOI：
- doi:10.5061/dryad.vr4sk
- 摘要：
- compensatory mechanism is modelled using a reciprocal temperature factor in the firing response function in the neural mass model. We demonstrate that the complete model
Data from: A novel open access web portal for integrating mechanistic and toxicogenomic study results
- 负责人：
- DOI：
- doi:10.5061/dryad.159h65k
- 摘要：
- , leading to relevant mechanistic conclusions. We describe its application by analyzing the effects of several toxicants on liver
Culturele Veranderingen in Nederland 1994 - CV'94;;Cultural changes in the Netherlands 1994 - CV'94
- 负责人：
- Stoop, I.A.L.;;Sociaal En Cultureel Planbureau, SCP * Den Haag (Research Initiator);;Nederlands Instituut Voor Publieke Opinie En Marktonderzoek
- 关键词：
- Social sciences Sociology employment conservatism economics family life gender roles values and beliefs politics social welfare
- DOI：
- doi:10.17026/dans-xmn-d4k6
- 摘要：
- , handicapped / social contacts / egoism - altruism / life satisfaction / prosperity: in this country, in own family, in future, government cares enoug
Data from: Selection history and epistatic interactions impact dynamics of adaptation to novel environmental stresses
- 负责人：
- DOI：
- doi:10.5061/dryad.85dn7
- 摘要：
- -free environments, we observed that accumulation of resistance mechanisms was accompanied by a reduction in overall fitness costs. We suggest tha
Data from: The yeast mitochondrial pyruvate carrier is a hetero-dimer in its functional state
- 负责人：
- DOI：
- doi:10.5061/dryad.m173s71
- 摘要：
- ng the structure of the functional complex and the mechanism of substrate transport and inhibition.
Antimalarial activity, toxicity, pharmacokinetics and metabolic drug interaction of Plumbago Indica linn.
- 负责人：
- Kesara Na-Bangchang, Advisor
- 关键词：
- Plumbagin Antimalarial Plasmodium falciparum Plasmodium berghei Permeability Transport Efflux transporters Caco-2 cell P-glycoprotein Pharmacokinetics
- DOI：
- doi:10.14457/tu.the.2015.159
- 摘要：
- of plumbagin across the Caco-2 cell monolayer in both directions. The transport mechanism is likely to be a passive transport. The propensity to inhibit CYP
Data from: Benefits of an anti-parasite treatment are influenced by within-brood size variation in Tree Swallows (Tachycineta bicolor)
- 负责人：
- DOI：
- doi:10.5061/dryad.zs7h44j51
- 摘要：
- m, anti-parasite drug, ivermectin (IVM), to?treat individual nestling Tree Swallows (Tachycineta bicolor) and assess how nestling suscepti
Data from: Survival of the feces: does a nematode lungworm adaptively manipulate the behavior of its cane toad host?
- 负责人：
- DOI：
- doi:10.5061/dryad.3p5r6
- 摘要：
- on or as nonadaptive consequences of infection on host physiology. However, the mechanisms by which lungworms alter cane toad thermal preference and defecati
Data from: Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending
- 负责人：
- DOI：
- doi:10.5061/dryad.3n39r6k
- 摘要：
- ors of drug-induced liver injury, but nothing is known concerning environmental pollutants. We aimed to study the impact of polycyclic aromatic hydrocarbons (PAHs), major
