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Data from: Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery
- 负责人：
- DOI：
- doi:10.5061/dryad.8r351
- 摘要：
- in order to determine their possible mechanisms of action. This effort has resulted in the identification of novel compounds and their hypothesized targets
Data from: Self-assembly behaviors of peptide-drug conjugates: influence of multiple factors on aggregate morphology and potential self-assembly
- 负责人：
- DOI：
- doi:10.5061/dryad.ft7c7
- 摘要：
- ular design, assembly time, pH and hydrogen bond inhibitor. On the basis of experimental results, we speculated the possible assembly mechanism of Ket-L-VEVE
Data from: Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC
- 负责人：
- DOI：
- doi:10.5061/dryad.67c92vm
- 摘要：
- that identifies mechanisms of action. We design and build a high-speed optical system to measure action potential, cytosolic calcium and contracti
Data from: Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs
- 负责人：
- DOI：
- doi:10.5061/dryad.86088n1
- 摘要：
- the neurobiological mechanism of neuropsychiatric drugs are not well reflected by their current classification or their chemical similarity, but can be better captured
Data from: Amphotericin B-conjugated polypeptide hydrogels as a novel innovative strategy for fungal infections
- 负责人：
- DOI：
- doi:10.5061/dryad.pc602
- 摘要：
- t the crystalline structure of the AmB and Dex are changed into amorphous structure after formation of hydrogels. Circular dichroism (CD) spectra of the solution of blank
Data from: Effect of canine oxytocin receptor gene polymorphism on the successful training of drug detection dogs
- 负责人：
- DOI：
- doi:10.5061/dryad.td13jp3
- 摘要：
- with an increased likelihood that a dog would successfully complete training. Although the molecular mechanism of the OXTR gene and its functional pathway rela
Data from: Immunotherapy-related adverse events (irAEs): extraction from FDA drug labels and comparative analysis
- 负责人：
- DOI：
- doi:10.5061/dryad.fg6kt38
- 摘要：
- Objectives: Immune checkpoint inhibitors (ICIs) have dramatically improved outcomes in cancer patients. However, ICIs are associated with signific
Data from: Diflunisal inhibits prestin by chloride-dependent mechanism
- 负责人：
- DOI：
- doi:10.5061/dryad.vq1dc
- 摘要：
- ir cells and for hearing. The only direct inhibitor of electromotility and the associated charge transfer is salicylate, possibly through direct interaction with an ani
The E3-ubiquitin ligase adaptor protein Skp1 is glycosylated by an evolutionarily conserved pathway that regulates protist growth and development.pdf
- 负责人：
- 关键词：
- 60102 Bioinformatics Cell Biology Microbiology Parasitology 60307 Host-Parasite Interactions 60502 Infectious Agents 110309 Infectious Diseases Pathology 60411 Population, Ecological and Evolutionary Genetics 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)
- DOI：
- doi:10.6084/m9.figshare.5505661.v1
- 摘要：
- to Dictyostelium Skp1, the mechanism may involve regulation of assembly of the SCF complex. Understanding the mechanism of Toxoplasma Skp1 glycosylation is expect
Data from: Enzymatic degradation of liquid droplets of DNA is modulated near the phase boundary
- 负责人：
- 关键词：
- DOI：
- doi:10.25349/D95G66
- 摘要：
- nt for cellular function. Analogous systems are studied as early-life compartmentalization mechanisms, for applications as protocells, or as drug-delivery vehicles. In ma
