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Data from: Bioprinted liver provides early insight into the role of Kupffer cells in TGF-?1 and methotrexate-induced fibrogenesis
负责人:
关键词:
DOI:
doi:10.5061/dryad.5rc1973
摘要:
r an extended exposure timeframe. Under these conditions, KCs were added to the model to examine their impact on the injury/fibrogenic response following cytokine
Data from: Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring
负责人:
关键词:
Parasitology;Life History Evolution;Virulence;Host Parasite Interactions;Evolutionary Medicine;Drug resistance;Disease Biology;Plasmodium chabaudi
DOI:
doi:10.5061/dryad.v244v
摘要:
parasite Plasmodium chabaudi differ substantially in their in vivo response to treatment. Slower clearance rates were not linked to parasite virulence or growth rate, going agains
Optogenetic control of genetically-targeted pyramidal neuron activity in prefrontal cortex
负责人:
关键词:
Physiology Neuroscience Molecular Biology Behavioral Neuroscience
DOI:
doi:10.6084/m9.figshare.91540.v2
摘要:
remained intact and patent for several weeks allowing us to establish stable maintenance of cocaine acquisition. This was followed by a dose response study
Data from: Rat retinal vasomotion assessed by laser speckle imaging
负责人:
Neganova, Anastasiia Y.
关键词:
Rat retina microcirculation vessels laser speckle
DOI:
doi:10.5061/dryad.163mp
摘要:
-acetylDL-penicillamine (SNAP). Although these drugs activate different cellular pathways responsible for vasomotion, our approach can track
Data from: Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC
负责人:
关键词:
excitation-contracting coupling;human pluripotent stem cell derived cardiomyocytes;drug testing;drug screening;human pluripotent stem cells
DOI:
doi:10.5061/dryad.67c92vm
摘要:
s on ion channels but they do not always accurately predict contractile responses of the human heart. This is in part attributable to their immaturity
Data from: Dynamics of cough frequency in adults undergoing treatment for pulmonary tuberculosis
负责人:
关键词:
Tuberculosis;airborne transmission;cough;Peru;infectiousness
DOI:
doi:10.5061/dryad.gv234
摘要:
of cough frequency throughout the day and in response to tuberculosis therapy. Here we evaluate the circadian cycle of cough; cough frequency risk factors
Data from: Genetic variation for antibiotic persistence in Escherichia coli
负责人:
关键词:
Genetic Variation;Escherichia coli;variation;Adaptation;Fitness;polymorphism;Population Biology
DOI:
doi:10.5061/dryad.h7d843j6
摘要:
Bacterial persistence describes a heterogenous response to antibiotics in clonal populations of bacteria due to phenotypic variation
Data from: The epileptology of alternating hemiplegia of childhood
负责人:
关键词:
MRI;Epilepsy\/Seizures;genetics;pediatric;MRS
DOI:
doi:10.5061/dryad.qn3287b
摘要:
awareness spells (RAS) occur frequently. 4) Epilepsy is commonly drug resistant but may respond to vagal nerve stimulation (VNS). 5) Status epilepticus (SE
Data from: Rapid quantitative pharmacodynamic imaging by a novel method: theory, simulation testing and proof of principle
负责人:
关键词:
fMRI;pharmacological fMRI;pharmacodynamics;phMRI;drug development;EC50;pharmacokinetic-pharmacodynamic modeling;ED50;neuroimaging;dose-finding
DOI:
doi:10.5061/dryad.s3443
摘要:
of drug that produces half the maximum possible effect). We first test the method with simulated data, assuming a typical sigmoidal dose-response
Data from: Cough frequency during treatment associated with baseline cavitary volume and proximity to the airway in pulmonary TB
负责人:
关键词:
CT;Tuberculosis;Mycobacteria;cough
DOI:
doi:10.5061/dryad.8pt77k0
摘要:
transmission and treatment response. Radiological characteristics associated with increased cough frequency may be important in understanding trans

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