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Data from: Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs
- 负责人：
- DOI：
- doi:10.5061/dryad.86088n1
- 摘要：
- drug effects are elusive. We use a big data approach from the neurotransmitter response patterns of 258 different neuropsychiatric drugs in rats to addres
Data from: Acquisition of conditioning between methamphetamine and cues in healthy humans
- 负责人：
- DOI：
- doi:10.5061/dryad.d2vf8
- 摘要：
- to four, had only modest effects on the strength of conditioned responses. Further studies investigating the parameters under which drug conditioning occurs
Data from: Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics
- 负责人：
- DOI：
- doi:10.5061/dryad.03n60
- 摘要：
- the molecular basis of therapeutic response and resistance. Here, we use them to investigate the relationship between different measures of drug sens
Data from: Cell death and survival due to cytotoxic exposure modeled as a two-state Ising system
- 负责人：
- DOI：
- doi:10.5061/dryad.4qrfj6q6d
- 摘要：
- methodology and apply it to a diverse panel of cytotoxic drugs administered against numerous cancer cell lines in a dose-response manner. The analyzed dataset was gene
Data from: Evolution of drug-tolerant nematode populations in response to density reduction
- 负责人：
- DOI：
- doi:10.5061/dryad.734c8
- 摘要：
- of resistance, including interactions between life-history traits and the strength of selection imposed by different drug-doses. We experimentally created
Data from: Modelling the evolution of HIV-1 virulence in response to imperfect therapy and prophylaxis
- 负责人：
- DOI：
- doi:10.5061/dryad.26767
- 摘要：
- virulence evolution in response to ‘leaky’ therapy (treat- ment that imperfectly suppresses viral replication) and the use of preventive drugs (pre-expo
Data from: Financial conflicts of interest of clinicians making submissions to the panCanadian Oncology Drug Review: a descriptive study
- 负责人：
- DOI：
- doi:10.5061/dryad.qs41mg4
- 摘要：
- disagreed with that recommendation. The distribution of clinician responses was statistically significantly different depending on whether pCODR recommended
Data from: Inhibition of histone deacetylases facilitates extinction and attenuates reinstatement of nicotine self-administration in rats
- 负责人：
- DOI：
- doi:10.5061/dryad.v77cn
- 摘要：
- s provide the first demonstration that HDAC inhibition facilitates the extinction of responding for an intravenously self-administered drug of abuse and furt
Data from: Evolutionary prediction of medicinal properties in the genus Euphorbia L.
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.s2df3
- 摘要：
- s of the human body and only poorly reflect biological responses to the treatment. Here we show that medicinal plant uses interpreted from a persp
Data from: Quantitative trait transcripts for nicotine resistance in Drosophila melanogaster
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.1030
- 摘要：
- en for abundance of ornithine aminotransferase transcripts, implicating detoxification and neurotransmitter biosynthesis as mediators of the quantitative response
