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Data from: Association of serum neurofilament light (sNfL) and disease severity in patients with spinocerebellar ataxia type 3
负责人:
关键词:
Spinocerebellar ataxia type-3;neurofilament light protein;biomarker
DOI:
doi:10.5061/dryad.n8pk0p2s2
摘要:
;">Methods:?This cross-sectional study enrolled 185 healthy controls and 235 ATXN3 mutation carriers (17 asymptomatic stage, 20 preclinical
Data from: Distinct BOLD fMRI responses of capsaicin-induced thermal sensation reveal pain-related brain activation in nonhuman primates
负责人:
Asad, Abu Bakar Ali
关键词:
fMRI capsaicin biomarker nonhuman primate pain imaging
DOI:
doi:10.5061/dryad.2gp4g
摘要:
preclinical research to clinical investigation. Many behavioral and self-report studies of pain have exploited the use of the capsaicin pain model
Data from: Mechanical conflict system: a novel operant method for the assessment of nociceptive behavior
负责人:
关键词:
pain;rat;affect;pregabalin;RP67580;substance P;morphine
DOI:
doi:10.5061/dryad.qs626
摘要:
A new operant test for preclinical pain research, termed the Mechanical Conflict System (MCS), is presented. Rats were given a choice either
Data from: Aberrant activation of the RANK signaling receptor induces murine salivary gland tumors
负责人:
关键词:
salivary gland;mouse;proliferation;overexpression;cancer prevention;RANK-Fc;transgenic;tumorigenesis;Receptor of activated NF-kB ligand
DOI:
doi:10.5061/dryad.qh3mm
摘要:
insufficiency is further exacerbated by a paucity of preclinical mouse models (as compared to other cancer fields) with which to both study sali
Data from: ATN profiles among cognitively normal individuals and longitudinal cognitive outcomes
负责人:
关键词:
Cognitive neuropsychology in dementia;Cohort studies;cerebrospinal fluid;Cognitive aging;Alzheimer's disease
DOI:
doi:10.5061/dryad.88br3tn
摘要:
and to stage AD across its preclinical and symptomatic phases. Applying this framework requires a large number of participants since the framework envisions ei
Data for: Effect of Source Animal Age upon Macrophage Response to Extracellular Matrix Biomaterials
负责人:
LoPresti, Samuel
关键词:
Bioengineering
DOI:
doi:10.17632/6pk288w982.1
摘要:
Extracellular matrix biomaterials have been shown to promote constructive remodeling in many preclinical and clinical applications. This response ha
Data from: A within-animal comparison of skilled forelimb assessments in rats
负责人:
关键词:
Force Strength Forelimb Ischemic Lesion Stroke Skilled Reaching Operant Behavior Pasta Matrix Isometric Pull
DOI:
doi:10.5061/dryad.5v2t8
摘要:
pull task represents an efficient, sensitive measure of forelimb function to facilitate preclinical evaluation in models of neurological injury
A percutaneously implantable wireless neurostimulator for treatment of stress urinary incontinence
负责人:
关键词:
Biomedical Engineering stress urinary incontinence neurostimulation implant wireless pelvic floor muscle training motor axon non-hermetic packaging minimal invasiveness
DOI:
doi:10.25549/usctheses-c40-436304
摘要:
or smartphone to prescribe exercise patterns and control and record daily use via Bluetooth communication to the seat cushion. ? Preclinical testing demonstrated
Data from: Body mass index, diet, physical inactivity and the incidence of dementia in one million UK women
负责人:
关键词:
Risk factors in epidemiology;Vascular dementia;Cohort studies;Alzheimer's disease;Cognitive Disorders\/Dementia
DOI:
doi:10.5061/dryad.3s755j8
摘要:
oaching null after 15 years. Conclusions: Mid-life obesity may well be a cause of dementia. In contrast, behavioural changes due to preclinical disease could

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