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Data from: Phylogenetic tree estimation with and without alignment: new distance methods and benchmarking
- 负责人:
- DOI:
- doi:10.5061/dryad.n5r49
- 摘要:
- d on the two-step process of multiple sequence alignment followed by tree inference, despite persistent evidence that the alignment step can lead to biased results. Her
Data from: Not all sequence tags are created equal: designing and validating sequence identification tags robust to indels
- 负责人:
- DOI:
- doi:10.5061/dryad.4m0v8474
- 摘要:
- Ligating adapters with unique synthetic oligonucleotide sequences (sequence tags) onto individual DNA samples before massively parallel sequencing
Data from: Simple chained guide trees give poorer multiple sequence alignments than inferred trees in simulation and phylogenetic benchmarks
- 负责人:
- DOI:
- doi:10.5061/dryad.4r5b8
- 摘要:
- Multiple sequence aligners typically work by progressively aligning the most closely related sequences or group of sequences according to guide trees
Data from: SNPdryad: predicting deleterious non-synonymous human SNPs using only orthologous protein sequences
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.n7m28
- 摘要:
- h prediction algorithms depends on the quality of the multiple-sequence alignment, which is used to infer how an amino acid substitution is tolerated at a given position
Data from: Current methods for automated filtering of multiple sequence alignments frequently worsen single-gene phylogenetic inference
- 负责人:
- DOI:
- doi:10.5061/dryad.pc5j0
- 摘要:
- Phylogenetic inference is generally performed on the basis of multiple sequence alignments (MSA). Because errors in an alignment can lead to errors
Data from: A simulation-based approach to statistical alignment
- 负责人:
- DOI:
- doi:10.5061/dryad.p069231
- 摘要:
- . Finally, it allows computing the maximum-likelihood alignment, the probability of a given pair of sequences integrated over all possible alignment
nchor: a novel approach for whole-genome comparative mapping utilising evolutionarily conserved DNA sequences"" data-category="" data-cropid="" data-dimen="" data-id="259A5B2C-B6B6-492D-834C-D41955585C5A"> Supporting data for "G-Anchor: a novel approach for whole-genome comparative mapping utilising evolutionarily conserved DNA sequences"
- 负责人:
- 关键词:
- Genome-Mapping Metabolomic Software Workflow whole-genome alignment sequence mapping sequencing anchoring highly conserved elements (hce) genome evolution
- DOI:
- doi:10.5524/100415
- 摘要:
- Cross-species whole-genome sequence alignment is a critical first step for genome comparative analyses ranging from the detection
Data from: Multiple sequence alignment averaging improves phylogeny reconstruction
- 负责人:
- DOI:
- doi:10.5061/dryad.4j1qt
- 摘要:
- The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps. First, a multiple sequence alignment (MSA
Data from: Construction of a virtual Mycobacterium tuberculosis consensus genome and its application to data from a next generation sequencer
- 负责人:
- 关键词:
- phylogenetic analysis;Mycobacterium tuberculosis;consensus sequence;virtual typing;SNP concatemer
- DOI:
- doi:10.5061/dryad.nq070
- 摘要:
- of the M. tuberculosis complexes (MTBCs) strains available on databases were aligned to construct virtual reference genome sequences called the consensus sequence (CS
Data from: Aligner optimization increases accuracy and decreases compute times in multi-species sequence data
- 负责人:
- DOI:
- doi:10.5061/dryad.m1m0p
- 摘要:
- , we observed important and adverse differences in alignment specificity and computation time for bwa- mem (Burrows–Wheeler aligner-maximum exact matches