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hout evolution despite frequent loss of RGS proteins in plants
- 负责人:
- DOI:
- doi:10.5061/dryad.4jp82
- 摘要:
- was proposed to enable the loss of RGS in monocots. We used a combination of evolutionary and biochemical analyses and homology modeling of the G? and RGS proteins
Data from: Sequence co-evolution gives 3D contacts and structures of protein complexes
- 负责人:
- DOI:
- doi:10.5061/dryad.6t7b8
- 摘要:
- ons is the evolutionary sequence record. Building on earlier work, we show that analysis of correlated evolutionary sequence changes across proteins identifies residues tha
Data from: Protein structure determination using metagenome sequence data
- 负责人:
- DOI:
- doi:10.5061/dryad.27p4s
- 摘要:
- of comparative modeling. We show that Rosetta structure prediction guided by residue-residue contacts inferred from evolutionary information can accurately model proteins
Data from: Strong selection significantly increases epistatic interactions in the long-term evolution of a protein
- 负责人:
- DOI:
- doi:10.5061/dryad.q66s5
- 摘要:
- Epistatic interactions between residues determine a protein’s adaptability and shape its evolutionary trajectory. When a protein
Data from: Viruses are a dominant driver of protein adaptation in mammals
- 负责人:
- DOI:
- doi:10.5061/dryad.fs756
- 摘要:
- of the most dominant drivers of evolutionary change across mammalian and human proteomes.
Data from: Snake venoms are integrated systems, but abundant venom proteins evolve more rapidly
- 负责人:
- DOI:
- doi:10.5061/dryad.3948r
- 摘要:
- , was barely present in the P. flavoviridis transcriptome (<0.05 %). Hybrids produced most proteins found in both parental venoms. Protein evolutionary rates wer
Data from: On the ancestral recruitment of metalloproteinases into the venom of snakes
- 负责人:
- DOI:
- doi:10.5061/dryad.fd5q0p68
- 摘要:
- Tracing the evolutionary history of proteins can reveal insights into gene alterations responsible for changes in structure and function. Her
Data from: An improved hypergeometric probability method for identification of functionally linked proteins using phylogenetic profiles
- 负责人:
- DOI:
- doi:10.5061/dryad.m6t4j
- 摘要:
- of proteins encoded in genomes. Here we propose an improved phylogenetic profile-based method which considers the co-evolution of the reference genome
Data from: Membrane proteins are dramatically less conserved than water-soluble proteins across the tree of life
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.00731
- 摘要:
- ria, and eukaryotes. Our findings point to a fundamental evolutionary principle: membrane proteins evolve faster due to stronger adaptive selecti
Data from: Neofunctionalization within the Omp85 protein superfamily during chloroplast evolution
- 负责人:
- DOI:
- doi:10.5061/dryad.r47q769s
- 摘要:
- in other systems. To elucidate the evolutionary relationship between the two proteins, we conducted a phylogenetic analysis using 48 sequences from diverse