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Data from: Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials
负责人:
关键词:
Consensus;Amyotrophic Lateral Sclerosis;guidelines;modified Delphi process;Clinical Trials
DOI:
doi:10.5061/dryad.32q9q5d
摘要:
Objective: To revise the 1999 Airlie House consensus guidelines for the design and implementation of preclinical therapeutic studies
Data from: Non-industry sponsored preclinical studies on statins yield greater efficacy estimates than industry-sponsored studies: a meta-analysis
负责人:
关键词:
animal experimentation risk of bias conflict of interests meta-analysis
DOI:
doi:10.5061/dryad.754d0
摘要:
in the methods used. However, the influence of sponsorship bias has not been examined in preclinical animal studies. We performed a meta-analysis of preclinical
Data from: The relationship between risk of bias criteria, research outcomes, and study sponsorship in a cohort of preclinical thiazoli
负责人:
关键词:
preclinical bias meta-analysis conflict of interest
DOI:
doi:10.5061/dryad.4c2bj
摘要:
Introduction: There is little evidence regarding the influence of conflicts of interest on preclinical research. This study examines whether
Analysis and visualization of multi-mode optical spectral-signature bioimaging data for in vivo applications
负责人:
关键词:
Biomedical Engineering multi-mode imaging spectral signature imaging hyperspectral imaging fluorescence lifetime imaging
DOI:
doi:10.25549/usctheses-m809
摘要:
in vivo imaging.; The usefulness of our new image analysis and visualization methods is demonstrated for selected preclinical research cases, including rat nec
Data from: Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer
负责人:
关键词:
DOI:
doi:10.5061/dryad.44j0zpc9v
摘要:
b preclinical pharmacology data support its therapeutic potential in CDK9- or CDK2-dependent cancers and as a rational combination with BCL2 inhibitors
Data from: Preclinical toxicity and pharmacokinetics of a new orally bioavailable flubendazole formulation and the impact for clinical trials and r
负责人:
Lammens, Lieve
关键词:
flubendazole toxicity pharmacokinetics risk/benefit
DOI:
doi:10.5061/dryad.5vv774m
摘要:
on these results, in combination with previously described genotoxicity and reproductive toxicity data and the outcome of the preclinical efficacy studies
Data from: Bio-inspired imager improves sensitivity in near-infrared fluorescence image-guided surgery
负责人:
关键词:
fluorescence;image guided surgery;imagers
DOI:
doi:10.5061/dryad.q6188pm
摘要:
accuracy compared to clinical imaging systems in current use. Preclinical and clinical data demonstrate that this technology seamlessly integrates int
Data from: A systems toxicology approach for the prediction of kidney toxicity and its mechanisms in vitro
负责人:
关键词:
Kidney toxicity;In Vitro and Alternatives;Prediction;mechanisms;Systems Toxicology
DOI:
doi:10.5061/dryad.646v2r1
摘要:
dated by their ability to accurately predict kidney toxicity of 4 out of 6 candidate therapeutics that exhibited toxicity only in in late stage preclinical
FAIRsharing record for: CDISC Define eXtensible Markup Language;;CDISC Define-XML
负责人:
关键词:
Biomedical Science Preclinical Studies
DOI:
doi:10.25504/fairsharing.yr61md
摘要:
of this description is the metadata record on FAIRsharing.org, an educational and informative resource that describes and links databases, standards, and data polic
FAIRsharing record for: Reporting guidElines For randomized controLled trials for livEstoCk and food safeTy;;REFLECT
负责人:
关键词:
Life Science Nutritional Science Preclinical Studies Safety study Group randomization
DOI:
doi:10.25504/fairsharing.tv1yg0
摘要:
, an educational and informative resource that describes and links databases, standards, and data policies. FAIRsharing also creates collections of these resources

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