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Data from: Complex evolution of insect insulin receptors and homologous decoy receptors, and functional significance of their multiplicity
- 负责人:
- 关键词:
- insulin signaling;insulin receptor;decoy of insulin receptor;wing polyphenism;gene structure;insects
- DOI:
- doi:10.5061/dryad.4xgxd255n
- 摘要:
- Evidence accumulates that the functional plasticity of insulin and insulin-like growth factor signaling in insects could spring, among others, from
Data from: Prolonged fasting-induced metabolic signatures in human skeletal muscle of lean and obese men
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.6121hj7
- 摘要:
- insulin signaling, and reduced levels of glucose-6-phosphate and TCA-cycle intermediates. 72h of fasting in lean participants reduced insulin-stimulated
Data from: Insulin signaling’s role in mediating tissue-specific nutritional plasticity and robustness in the horn-polyphenic beetle
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.35g4j2q
- 摘要:
- remain poorly understood. We assessed the functions of members of the insulin/insulin-like signaling pathway (IIS) in the regulation of nutrition
Data from: Protective role of nano-selenium-enriched Bifidobacterium longum in delaying the onset of streptozotocin-induced diabetes
- 负责人:
- DOI:
- doi:10.5061/dryad.v4g40ms
- 摘要:
- on of insulin signaling pathway-related proteins was evaluated by western blotting. Hematoxylin and eosin (H&E) was used for histological examination of the liver, pancreas
Data from: A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila
- 负责人:
- DOI:
- doi:10.5061/dryad.8f0r6j9
- 摘要:
- clinal SNPs in insulin/insulin-like growth factor signaling (IIS), a pathway known from mutant studies to affect life history. However, the effect
Data from: Caenorhabditis elegans genes affecting interindividual variation in life-span biomarker gene expression
- 负责人:
- DOI:
- doi:10.5061/dryad.m55h6
- 摘要:
- erest to determine how interindividual differences in biomarker gene expression arise. Prior reports showed that the thermosensory neurons and insulin signaling
Data from: Immune response and insulin signalling alter mosquito feeding behaviour to enhance malaria transmission potential
- 负责人:
- DOI:
- doi:10.5061/dryad.qn765
- 摘要:
- changes are functionally linked to changes in insulin signalling in the mosquito gut. These results suggest that altered phenotypes derive from
Data from: Stage-specific plasticity in ovary size is regulated by insulin/insulin-like growth factor and ecdysone signalling in Drosophila
- 负责人:
- 关键词:
- critical period for environmental sensitivity ecdysone signaling insulin/insulin-like growth factor signaling larval nutrition ovary size
- DOI:
- doi:10.5061/dryad.688nk
- 摘要:
- /insulin-like growth factor and the ecdysone-signaling pathways, modulate the timing and rates of all three developmental processes. The change in sensitivity in the ovary res
Data from: Hyperandrogenism and insulin resistance induce gravid uterine defects in association with mitochondrial dysfunction and aberrant
- 负责人:
- DOI:
- doi:10.5061/dryad.3d63vh5
- 摘要:
- , Angpt1, Angpt2, Ho1, Ccl2, Ccl5, Cxcl9, and Cxcl10) and insulin signaling (Akt, Gsk3 and Gluts). Moreover, we observed changes in uterine
Data from: Rapid molecular evolution across amniotes of the IIS/TOR network
- 负责人:
- DOI:
- doi:10.5061/dryad.vn872
- 摘要:
- hts and interventions into disease. The insulin/insulin-like signaling and target of rapamycin (IIS/TOR) molecular network regulates metabolism, growth, and aging