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Data from: Evaluation of the innate immunostimulatory potential of originator and non-originator copies of insulin glargine in an in vitro human
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.6hf1pc1
- 摘要：
- copies of insulin glargine for innate immune activity and mechanisms leading to differences in these response profiles in an in vitro model of human
Data from: Life in the fat lane: seasonal regulation of insulin sensitivity, food intake, and adipose biology in brown bears
- 负责人：
- DOI：
- doi:10.5061/dryad.sc38b
- 摘要：
- g within the hypothalamus of hibernating bears; labeling virtually disappeared in active bears. Adipocytes collected during hibernation were insulin resistant when cultured
Data from: Hyperandrogenism and insulin resistance induce gravid uterine defects in association with mitochondrial dysfunction and aberrant
- 负责人：
- DOI：
- doi:10.5061/dryad.3d63vh5
- 摘要：
- r actions in the uterus during pregnancy are well understood. We hypothesised that hyperandrogensim and insulin resistance exert a causative role
Data from: Hyperandrogenism and insulin resistance-induced fetal loss: evidence for placental mitochondrial abnormalities and elevated ROS producti
- 负责人：
- 关键词：
- Mitochondria;reactive oxygen species;Placenta;fetal loss;Oxidative stress;Polycystic ovary syndrome
- DOI：
- doi:10.5061/dryad.30bf364
- 摘要：
- gate the impact of hyperandrogenism and insulin resistance on fetal survival and to determine the molecular link between PCOS conditions and placental dysfuncti
Data from: A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila
- 负责人：
- DOI：
- doi:10.5061/dryad.8f0r6j9
- 摘要：
- clinal SNPs in insulin/insulin-like growth factor signaling (IIS), a pathway known from mutant studies to affect life history. However, the effects
Data from: Hypoglycemia Following intravenous insulin plus glucose for hyperkalemia in patients with impaired renal function
- 负责人：
- DOI：
- doi:10.5061/dryad.m51q0
- 摘要：
- an intravenous infusion of insulin plus glucose to treat hyperkalemia. Methods: We retrospectively reviewed charts of all AKI and non-dialysis dependent CKD pati
Data from: Ablation of insulin-producing cells prevents obesity but not premature mortality caused by a high-sugar diet in Drosophila
- 负责人：
- DOI：
- doi:10.5061/dryad.t04v4
- 摘要：
- , by genetic ablation of median neurosecretory cells (mNSCs) that produce insulin-like peptides, extends lifespan and counteracts the detrimental effects
Data from: A highly pleiotropic amino acid polymorphism in the Drosophila insulin receptor contributes to life history adaptation
- 负责人：
- DOI：
- doi:10.5061/dryad.057r9
- 摘要：
- in allele frequency concurrent with seasonal change. We tested the alleles for effects on levels of insulin signaling, fecundity, development time, body size
Data from: An investigation of the therapeutic effects of statins with metformin on polycystic ovary syndrome: a meta-analysis
- 负责人：
- DOI：
- doi:10.5061/dryad.54sg8
- 摘要：
- to identify the effects of statins: clinical variables, metabolic characteristics, hormone outcomes, sign of inflammation, glucose parameters and insulin
Data from: Modelling of dysregulated glucagon secretion in type 2 diabetes by considering mitochondrial alterations in pancreatic alpha cells
- 负责人：
- DOI：
- doi:10.5061/dryad.9n2k1vk
- 摘要：
- as the disease progresses. However, clinical treatments based solely on insulin secretion and action have had limited success. The focus is therefore shifting towa
