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Data from: The early spread and epidemic ignition of HIV-1 in human populations
- 负责人：
- 关键词：
- 20th century;phylogeography;Human Immunodeficiency Virus Type 1;Phylodynamics;population dynamics
- DOI：
- doi:10.5061/dryad.nn952
- 摘要：
- Thirty years after the discovery of HIV-1, the early transmission, dissemination and establishment of the virus in human populations remain unclear
Data from: 1970s and ‘Patient 0’ HIV-1 genomes illuminate early HIV/AIDS history in North America
- 负责人：
- DOI：
- doi:10.5061/dryad.7mv7v
- 摘要：
- The emergence of HIV-1 group M subtype B in North American men who have sex with men was a key turning point in the HIV/AIDS pandemic. Phylogenetic
Data from: Geographically-stratified HIV-1 group M pol subtype and circulating recombinant form sequences
- 负责人：
- DOI：
- doi:10.5061/dryad.56j2n
- 摘要：
- Accurate classification of HIV-1 group M lineages, henceforth referred to as subtyping, is essential for understanding global HIV-1
Data from: Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis
- 负责人：
- DOI：
- doi:10.5061/dryad.7h46hg2
- 摘要：
- To prevent new infections with human immunodeficiency virus type 1 (HIV-1) in sub-Saharan Africa, UNAIDS recommends targeting interventions
Data from: Antibody selection and amino acid reversions
- 负责人：
- DOI：
- doi:10.5061/dryad.69mk7
- 摘要：
- the rate of adaptation. The model successfully predicts the rate of reversion per allele fixation for an important human immunodeficiency virus type 1 (HIV-1
Data from: Strong selection significantly increases epistatic interactions in the long-term evolution of a protein
- 负责人：
- DOI：
- doi:10.5061/dryad.q66s5
- 摘要：
- in the long-term evolution of a protein. Here we analyze the evolution of epistasis in the protease of the human immunodeficiency virus type 1 (HIV-1) using protease
Data from: First-in-human randomized controlled trial of an oral, replicating Adenovirus 26 vector vaccine for HIV-1
- 负责人：
- DOI：
- doi:10.5061/dryad.697r480
- 摘要：
- Background: Live, attenuated viral vectors that express HIV-1 antigens are being investigated as an approach to generating durable immune responses
Data from: A non-parametric analytic framework for within-host viral phylogenies and a test for HIV-1 founder multiplicity
- 负责人：
- DOI：
- doi:10.5061/dryad.33m05qb
- 摘要：
- ), temporal changes in substitution rates, mutational fitness, and time between sampling. Using sequences from individuals infected with HIV-1, we showed the utility
Data from: The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies
- 负责人：
- DOI：
- doi:10.5061/dryad.66h5g23t
- 摘要：
- BACKGROUND: The conserved CD4 binding site (CD4bs) on HIV-1 gp120 is a major target for vaccines. It is a priority to determine sites and structures
Data from: Selection analyses of paired HIV-1 gag and gp41 sequences obtained before and after antiretroviral therapy
- 负责人：
- DOI：
- doi:10.5061/dryad.71b5t
- 摘要：
- Most HIV-1-infected individuals with virological failure (VF) on a pharmacologically-boosted protease inhibitor (PI)-containing regimen
