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Data from: Purifying selection in the toll-like receptors of song sparrows Melospiza melodia
- 负责人：
- Nelson-Flower, Martha
- 关键词：
- toll-like receptor immune gene diversity inbreeding coefficient survival negative selection Subject area: Molecular adaptation and selection
- DOI：
- doi:10.5061/dryad.10h01t1
- 摘要：
- ross animal taxa. Toll-like receptors (TLRs) comprise one essential gene family in the vertebrate innate immune system, and recognize evolutionarily conserved
Data from: Evolution of toll-like receptors in the context of terrestrial ungulates and cetaceans diversification
- 负责人：
- DOI：
- doi:10.5061/dryad.80p28
- 摘要：
- Background: Toll-like receptors (TLRs) are the frontline actors in the innate immune response to various pathogens and are expected to be targets
Data from: Polymorphisms at the innate immune receptor TLR2 are associated with Borrelia infection in a wild rodent population
- 负责人：
- Tschirren, Barbara
- DOI：
- doi:10.5061/dryad.16h1t
- 摘要：
- The discovery of the key role of Toll-like receptors (TLRs) in initiating innate immune responses and modulating adaptive immunity has revolutionised
Data from: Repurposed transcriptomic data facilitate discovery of innate immunity Toll-Like Receptor (TLR) genes across Lophotrochozoa
- 负责人：
- DOI：
- doi:10.5061/dryad.0318j
- 摘要：
- e initially collected for another purpose. Here, we use transcriptomes collected for phylogenomic studies to search for toll-like receptor (TLR) genes in po
Data from: Down-regulation of CXCL12/CXCR4 expression alleviates ischemia-reperfusion-induced inflammatory pain via inhibiting glial TLR4 activation
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.5934k
- 摘要：
- Toll-like receptor 4 (TLR4) is important for the pathogenesis of inflammatory reactions and the promotion of pain processing after ischemia
Data from: Reduced PICD in monocytes mounts altered neonate immune response to Candida albicans
- 负责人：
- DOI：
- doi:10.5061/dryad.7t4b1
- 摘要：
- monocytes (PBMO) due to lower stimulation of TLR-mediated immune responses. Methods: The ability to phagocytose C. albicans, expression of TLRs, the induction
Data from: Signatures of selection acting on the innate immunity gene Toll-like receptor 2 (TLR2) during the evolutionary history of rodents
- 负责人：
- DOI：
- doi:10.5061/dryad.8631
- 摘要：
- of the innate immune system of vertebrates, the Toll-like receptor 2 (TLR2), across 17 rodent species. Although purifying selection was the prevalent evolutionary force acting
Data from: Immunogenetic heterogeneity in a widespread ungulate: the European roe deer (Capreolus capreolus)
- 负责人：
- DOI：
- doi:10.5061/dryad.3vb7h
- 摘要：
- in a panel of genes involved in innate and acquired immunity in roe deer, including Mhc-Drb and genes encoding cytokines or toll-like receptors (TLRs). Toge
Data from: Macroparasites at peripheral sites of infection are major and dynamic modifiers of systemic anti-microbial pattern recognition responses
- 负责人：
- DOI：
- doi:10.5061/dryad.s7t1g
- 摘要：
- anti-microbial pattern recognition receptors (PRRs) such as toll-like receptors (TLRs). Whilst PRR-mediated response programmes are the result of lon
Data from: Contracting patterns of diversity and population differentiation at the innate immunity gene Toll-like receptor 2 (TLR2) in two sympatric
- 负责人：
- DOI：
- doi:10.5061/dryad.744v6t51
- 摘要：
- ross vertebrate populations. Here, we present a study on the diversity and population differentiation at the innate immune gene Toll-like receptor 2 (TLR2) ac
