Data from: Nrf2 ameliorates DDC-induced sclerosing cholangitis and biliary fibrosis and improves the regenerative capacity of the liver.

负责人：

Fragoulis, Athanassios

关键词：

cre validation supporting data/analyses

DOI：

doi:10.5061/dryad.d8vs845

摘要：

The Nrf2 pathway protects against oxidative stress and induces regeneration of various tissues. Here, we investigated whether Nrf2 protects from

Data from: Acetaminophen responsive miR-19b modulates SIRT1/Nrf2 signaling pathway in drug-induced hepatotoxicity

负责人：

关键词：

DOI：

doi:10.5061/dryad.sm12b53

摘要：

exacerbated APAP-induced oxidative stress and liver injury, especially reduction of Nrf2 and subsequent downregulation of several antioxidant genes

Data from: Proteomic analysis reveals a predominant NFE2L2 (NRF2) signature in the ?canonical pathway and upstream regulator analysis of Leishmania

负责人：

关键词：

Mus musculus;Leishmania amazonensis;Leishmania major

DOI：

doi:10.5061/dryad.tr4185n

摘要：

the infection process. NRF2 signatures were present in both CPs and UTFs pathways. Proteins involved in iron metabolism, such as heme oxigenase 1 (HO-1) and ferritin besi

SKN-1 coordination of stress adaptation, metabolism, and resource allocation in Caenorhabditis elegans

负责人：

关键词：

Nrf2 Molecular Biology SKN-1 Asdf metabolism stress response resource allocation lipids high carbohydrate diet ALH-6

DOI：

doi:10.25549/usctheses-c40-260305

摘要：

by the cytoprotective transcription factor SKN-1/Nrf2, which integrates diet composition and availability with utilization for survival. These responses have potent

Data from: Hyperandrogenism and insulin resistance-induced fetal loss: evidence for placental mitochondrial abnormalities and elevated ROS production in pregnant rats that mimic the clinical features of PCOS

负责人：

关键词：

Mitochondria;reactive oxygen species;Placenta;fetal loss;Oxidative stress;Polycystic ovary syndrome

DOI：

doi:10.5061/dryad.30bf364

摘要：

of reactive oxygen species (ROS) in the placenta, mitochondrial dysfunction, and disturbed SOD1 and Keap1/Nrf2 antioxidant responses constitute important contributors to fetal loss

Data from: Hyperandrogenism and insulin resistance induce gravid uterine defects in association with mitochondrial dysfunction and aberrant ROS production

负责人：

关键词：

angiogenesis;mitochondrial homeostasis;reactive oxygen species;Uterine decidualization;Nrf2 signaling;Polycystic ovary syndrome

DOI：

doi:10.5061/dryad.3d63vh5

摘要：

, and mitophagy) and suppression of both oxidative and antioxidative defenses (i.e. reactive oxygen species, Nrf2 signaling, and interactive