PROBLEM TO BE SOLVED: To provide an oral care composition which prevents adhesion of oral bacteria, prevents formation of biofilm, has safety also to the so-called weak persons having vulnerable oral cavity which is sensitive to chemical stimulation, and can achieve high oral hygiene care.SOLUTION: We found out that the use of a composition containing a liposome containing cetylpyridinium chloride and non-hydrogenated phospholipid, or a liposome containing hydrogenated phospholipid can prevent bacteria, such as Streptococcus mutans or Staphylococcus aureus, from adhering to the surface of intraoral tissues or a denture to proliferate, and provides the oral care composition of the present application.COPYRIGHT: (C)2016,JPO&INPIT