The present invention relates to a drug delivery device for administering a dose of a medicament by way of injection, the device comprising: a housing (12, 14) to receive a cartridge at least partially filled with a medicament and being sealed with a piston slidably disposed therein, a drive mechanism having a piston rod to be displaced in a distal direction (32) to operably engage with the piston of the cartridge, an actuation means (16) operably engaged with the drive mechanism to prepare and/or to initiate a dose dispensing action of the drive mechanism, and a protective member (18； 38) adapted to impede actuation of the actuation means (16), wherein the protective member (18； 38) is releasably connected to the housing (12, 14) by means of a breakable seal (20, 40).
