Induction of mucosal tolerance to antigens

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专利权人:

アクトジェニックス・エヌブイ

发明人:

ロティエ，ピーテル,スノエック，フェールレ,ロティエ,ピーテル,スノエック,フェールレ

申请号：

JP2008542752

公开号：

JP5410759B2

申请日:

2006.11.29

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

The present invention relates to the induction of tolerance to antigens, by mucosal, preferably oral delivery of the antigen in combination with an immunomodulating compound producing micro-organism. More specifically, the invention relates to the induction of Foxp3 + and/or IL-10 and/or TGF-² producing regulatory T-cells, capable of suppressing undesired immune responses toward an antigen, by oral delivery of said antigen in combination with an immunosuppressing cytokine secreting micro-organism.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/