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Induction of mucosal tolerance to antigens
专利权人:
INTREXON ACTOBIOTICS NV
发明人:
Pieter Rottiers,Veerle Snoeck
申请号:
US14216842
公开号:
US09526750B2
申请日:
2014.03.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to the induction of tolerance to antigens, by mucosal, preferably oral delivery of the antigen in combination with an immunomodulating compound producing micro-organism. More specifically, the invention relates to the induction of Foxp3+ and/or IL-10 and/or TGF-β producing regulatory T-cells, capable of suppressing undesired immune responses toward an antigen, by oral delivery of said antigen in combination with an immunosuppressing cytokine secreting micro-organism.
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中国工程科技知识中心
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