COPPOLA, GARY MARK,KARKI, RAJESHRI GANESH,KAWANAMI, TOSHIO
申请号:
CA2817114
公开号:
CA2817114A1
申请日:
2011.11.14
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, A1, X, X1, s and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of the compounds of the invention and a combination of pharmacologically active agents and a compound of the invention.