ANTICORPS ANTI-PEPTIDES N3PGLU AMYLOIDES BETA ET UTILISATIONS ASSOCIEES

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专利权人:

ELI LILLY AND COMPANY

发明人:

DEMATTOS, RONALD BRADLEY,IRIZARRY, MICHAEL CARL

申请号：

CA3029550

公开号：

CA3029550A1

申请日:

2017.06.23

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The invention is directed to a short term induction treatment with anti-N3pGlu Aß antibodies of a disease characterized by deposition of Aß in the brain, that include Alzheimer's disease (AD), Down's syndrome, and cerebral amyloid angiopathy (CAA). In certain embodiments, patients are administered an induction dose of 10 to 60 mg/kg of an anti-N3pGlu Aß antibody for a period of 6 months or less.

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