ANTI-N3pGlu AMYLOID BETA PEPTIDE ANTIBODIES AND USES THEREOF

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专利权人:

Eli Lilly and Company

发明人:

Ronald Bradley Demattos,Michael Carl Irizarry

申请号：

US16310629

公开号：

US20190382471A1

申请日:

2017.06.23

申请国别(地区):

US

年份:

2019

代理人:

摘要：

The invention is directed to a short term induction treatment with anti-N3pGlu Aβ antibodies of a disease characterized by deposition of Aβ in the brain, that include Alzheimer's disease (AD), Down's syndrome, and cerebral amyloid angiopathy (CAA). In certain embodiments, patients are administered an induction dose of 10 to 60 mg/kg of an anti-N3pGlu Aβ antibody for a period of 6 months or less.

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