INJECTABLE SOLUTION AT PH 7, COMPRISING AT LEAST ONE BASAL INSULIN WITH A PI BETWEEN 5.8 AND 8.5, AT LEAST ONE IONIC SPECIES, AND AN AMPHIPHILIC COMPOUND BEARING HYDROPHOBIC RADICALS
The invention relates to a composition that is physically stable in the form of an injectable aqueous solution, the pH of which is between 6.0 and 8.0, comprising at least: - one basal insulin with an isoelectric point (pI) between 5.8 and 8.5, - at least one ionic species, and - an amphiphilic compound comprising a hydrophilic backbone HB substituted with at least one hydrophobic radical -Hy of formula I.L'invention concerne une composition stable physiquement sous forme d'une solution aqueuse injectable, dont le pH est compris entre 6,0 et 8,0, comprenant au moins - une insuline basale dont le point isoélectrique (pI) est compris entre 5,8 et 8,5, - au moins une espèce ionique et - un composé amphiphile comprenant un squelette hydrophile HB, substitué par au moins un radical hydrophobe -Hy de formule I.
