Recombinant clostridium botulinum neurotoxins

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专利权人:

Ipsen Bioinnovation Limited;Ipsen Biopharm Limited

发明人:

MARKS, Philip,COSSINS, Aimee,BEARD, Matthew

申请号：

DK13811605

公开号：

DK2914282T3

申请日:

2013.10.31

申请国别(地区):

DK

年份:

2018

代理人:

摘要：

The invention provides a nucleic acid sequence comprising a sequence of contiguous nucleotides, wherein said sequence of contiguous nucleotides has at least 90% sequence identity to the nucleic acid sequence of SEQ ID NO: 1, and wherein said sequence of contiguous nucleotides encodes a single-chain BoNT/El protein. The present invention also provides methods for producing soluble single-chain BoNT/E protein in an E. colihost cell, together with methods for producing soluble di-chain 10 BoNT/El protein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/