Recombinant clostridium botulinum neurotoxins

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专利权人:

Ltd.;Ipsen Biopharm, Ltd.;Ipsen Bioinnovation Limited;Ipsen Biopharm

发明人:

Cossins, Aimee,Beard, Matthew,Marks, Philip

申请号：

AU2013340610

公开号：

AU2013340610B2

申请日:

2013.10.31

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The invention provides a nucleic acid sequence comprising a sequence of contiguous nucleotides, wherein said sequence of contiguous nucleotides has at least 90% sequence identity to the nucleic acid sequence of SEQ ID NO: 1,and wherein said sequence of contiguous nucleotides encodes a single-chain BoNT/E1 protein. The present invention also provides methodsfor producing soluble single-chain BoNT/E protein in an E. colihost cell, together with methodsfor producing soluble di-chain 10 BoNT/E1 protein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/