A system for enhanced surgical navigation including a computing device and an imaging device. The computing device is configured to import a navigation path to a target using a first data set of computed tomography images previously acquired, display the navigation path on a graphical user interface for navigation to the target and placement of a plurality of markers in tissue proximate the target, and acquire a second data set of computed tomography images including the plurality of markers. The imaging device is configured to capture fluoroscopic data of tissue proximate the plurality of markers. The computing device is further configured to register the fluoroscopic data to the second data set of computed tomography images based on marker position and marker orientation within the fluoroscopic data and marker position and orientation within the second data set of computed tomography images.
