結合ＥＧＦＲ及ＭＥＴ之多功能抗體农业专利-农业学术服务平台

发明人:: ALDAZ, HECTOR,艾达斯　海克特,艾達斯　海克特,ALLAN, BARRETT,艾伦　巴瑞特,艾倫　巴瑞特,LIU, LING,刘　陵,劉　陵,LU, JIRONG,卢　吉让,盧　吉讓,TANG, YING,唐鹰,唐鷹,TSCHANG, SHENG-HUNG RAINBOW,詹　绅鸿　蓝宝,詹　紳鴻　藍寶,YACHI, PIA PAULIINA,亚奇　皮埃　波林娜,亞奇　皮埃　波林娜,艾达斯海克特,艾達斯海克特,艾伦巴瑞特,艾倫巴瑞特,刘陵,劉陵,卢吉让,盧吉讓,詹绅鸿蓝宝,詹紳鴻藍寶,亚奇皮埃波林娜,亞奇皮埃波林娜

摘要：: Provided are multifunctional antibodies, and/or antigen-binding fragments, that bind to, and inhibit the activity of, both human epidermal growth factor receptor (EGFR) and MET, and that are effective in treating cancers and other diseases, disorders, or conditions where pathogenesis is mediated by EGFR and MET.本發明提供多功能抗體及/或抗原結合片段，其等可結合至人類表皮生長因子受體(epidermal growth factor receptor；EGFR)及MET，並抑制EGFR及MET之活性，且可效治療癌症及發病機制由EGFR及MET介導之其他疾病、病症或病狀。