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METHOD FOR PRODUCING A DRUG DELIVERY SYSTEM ON THE BASIS OF POLYELECTROLYTE COMPLEXES
专利权人:
Martin Mueller
发明人:
Martin Mueller
申请号:
US13638413
公开号:
US20130108774A1
申请日:
2011.03.30
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to the fields of polymer chemistry, pharmacy and medicine and relates to a method, which for example releases drugs as a component of implants into the environment of the implant. The object of the present invention is to disclose a method which in a simple and easily reproducible manner generates a drug delivery system, which releases drugs in a locally targeted and controllably delayed manner. The object is attained by a method in which polyanions and polycations are mixed in a liquid in a non-stoichiometric ratio, relative to the charged monomer units, wherein drugs are added to the polyelectrolytes either before, during or after the mixing, or charge-carrying drugs and an oppositely charged polyelectrolyte are mixed, and after the mixing the polyelectrolyte complex produced is applied to the surface of a medical means or is positioned on the surface directly at the location where the drug is to be released.
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