The present invention relates to a syringe for treating facial wrinkles having a syringe cylinder, a needle body detachably mounted at the front end portion of the syringe cylinder and having a syringe needle disposed thereon, and a piston rod disposed inside the syringe cylinder for operating a piston, the syringe including: the syringe cylinder formed of a substantially thin tube having an inside diameter in a range of 2.0 mm to 7.0 mm and an inflow check valve disposed at one side of the front end portion of the syringe cylinder so as to supply a predetermined quantity of gas to the interior of the syringe cylinder, wherein the predetermined quantity of gas supplied through the inflow check valve to the interior of the syringe cylinder and a predetermined quantity of liquid filled into the syringe cylinder are injected in turn into the dermis of the skin, which is repeatedly carried out.