INSERM (Institut National de la Santé et de la Recherche Médicale)
发明人:
申请号:
EP09796378.9
公开号:
EP2358874B1
申请日:
2009.12.21
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to chimeric derivatives of serine protease zymogen containing the activation peptide of factor X or a fragment thereof for improving the half-life of said derivatives. Preferably, said chimeric derivatives are protein C and factor X derivatives. The invention also relates to said derivatives for the prevention or treatment of blood coagulation disorders.