LAU, Johnson Yiu-Nam,YEUNG, Philip Man Lung,CHAN, Fuk Woo Jasper,FOK, Manson,YUEN, Kwok-Yung
申请号：
EP17851466
公开号：
EP3512550A4
申请日:
2017.09.13
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Enteroviruses, such as EV-A71, have been found to utilize hWARS as a cell surface receptor, with expression ofhWARS rendering cells susceptible to enteroviral infection. Reduction in hWARS cell surface activity reduces susceptibility to enteroviral infection and provides a mode for treatment or prevention of enteroviral infection and its sequelae. Similarly, expression of hWARS in cultured cells and animal models provides models for understanding enteroviral disease mechanisms and the development of vaccines and/or pharmaceuticals for preventing or treating enteroviral disease.
