Sebastianus Gerardus Johannes Maria Kluijtmans,Elisabeth Marianna Wilhelmina Maria Van Dongen,Kendell Marleen Pawelec,Jonathan Knychala,Dennis Adrianus Verduijn
申请号:
US15759399
公开号:
US20190247543A1
申请日:
2016.09.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Composites and scaffolds suitable for bone void filling comprising at least a recombinant gelatin and hydroxyapatite in which the recombinant gelatin comprises glutamic and aspartic acid residues that are distributed homogeneously along a gelatin chain, wherein: (i) the recombinant gelatin comprises a total of at least a 8% glutamic and/or aspartic acids amount per 60 amino acids in row with a standard deviation of at most 1.6; (ii) the hydroxyapatite is obtained by precipitation in the presence of the recombinant gelatin.