ERTL, JOHANN,HABERMANN, PAUL,GEISEN, KARL,SEIPKE, GERHARD,WOLLMER, AXEL
申请号:
HU0102217
公开号:
HU228908B1
申请日:
1999.05.21
申请国别(地区):
HU
年份:
2013
代理人:
摘要:
The invention relates to insulin analogs exhibiting enhanced zinc binding capacity and to stable zinc complexes thereof having a retarded activity in comparison with human insulin. The invention further relates to a method for the production of said insulin analogs and to their use, particularly in pharmaceutical preparations for therapy of type I and type II diabetes mellitus.