SUNG YOUB JUNG,SE CHANG KWON,JUNG KUK KIM,DAE JIN KIM,YONG HO HEO,IN YOUNG CHOI
申请号：
DO2016000302
公开号：
DOP2016000302A
申请日:
2016.11.22
申请国别(地区):
DO
年份:
2016
代理人:
摘要：
The present Invention relates to a composition for the Prevention or treatment of Diabetes insulin conjugate Action includes a Prologue and an insulinotropic Peptide Conjugate of prolonged Action, and a method for treating diabetes.More specifically, the Administration of the combination of long-acting Analogue of the conjugate and the insulinotropic Peptide Conjugate of long-acting, inhibited the increase of weight due to insulin Administration, and nausea and vomiting due to management d The insulinotropic Peptide, and also reduces the required dose of insulinImproving the Observance of this form of the drug.In addition, the present Invention relates to the Administration of a Pharmaceutical composition for reducing side effects of pancreatic beta cells in diabetic patients, which includes a combination of long-acting insulin analogue and Analogue p u00e9pti Conjugate OJ insulinotropic Action prolongedAnd a method to reduce the side effects of pancreatic beta cells in diabetic patients, which includes the step of administering the composition.Specifically, the present Invention is characterized by the reduction of side effects such as the Abnormality in the function of pancreatic beta cells associated with development of diabetes, reducing the mass of pancreatic beta cells, or glucotoxicidad lipotoxicity.La presente invención se refiere a una composición para la prevención o tratamiento de la diabetes que incluye un conjugado de insulina de acción prologada y un conjugado de péptido insulinotrópico de acción prolongada, y un método para tratar la diabetes. Más específicamente, la administración de la combinación del conjugado de análogo de acción prolongada y el conjugado de péptido insulinotrópico de acción prolongada, inhibe el aumento de peso debido a la administración de insulina, y los vómitos y náuseas debidos a la administración del péptido insulinotrópico, y también reduce la dosis requerida de insulina, mejorando notablemente de esta forma la observancia
