テルミサルタンの製造方法

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专利权人:

株式会社トクヤマ

发明人:

宮奥 隆行,田中 健次

申请号：

JP2014179583

公开号：

JP6284861B2

申请日:

2014.09.03

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

PROBLEM TO BE SOLVED: To provide a method for highly controlling the amount of ethyl acetate contained in telmisartan with good productivity in a method for producing telmisartan effective as a hypotensive agent by mixing a solution containing an ammonium salt of telmisartan and ethyl acetate with an acetic acid.SOLUTION: In a method for producing telmisartan by mixing a solution containing an ammonium salt of telmisartan and ethyl acetate with an acetic acid to neutralize the ammonium salt of telmisartan, the amount of ethyl acetate in the solution is not less than 0.01 mol to not more than 7.0 mol based on 1 mol of the ammonium salt of telmisartan.SELECTED DRAWING: None

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/