PROBLEM TO BE SOLVED: To provide a therapeutic medicine for a neurodegenerative disease and psychiatric disease containing as effective components a low molecular compound having BDNF-like functions enabling to peripherally administer.SOLUTION: The therapeutic medicine for neurodegenerative disease and psychiatric disease includes a compound expressed by formula (1) or pharmaceutically permissive salts thereof as an effective component. In formula, A1 represents a phenyl group, pyridyl group, adamantyl group, 1-6C alkoxycarbonyl group or the like n denotes 0 or 1 L represents -C(=O)-N(R1)- or the like R1 represents H or 1-6C alkyl group or the like A2 represents a phenyl group, 3-7C cycloalkyl group or the like.COPYRIGHT: (C)2013,JPO&INPIT【課題】BDNF様作用を有する末梢投与可能な低分子化合物を有効成分として含む神経変性疾患治療薬および精神疾患治療薬を提供する。【解決手段】式(1)[式中、A1はフェニル基、ピリジル基、アダマンチル基、C1-6アルコキシカルボニル基等を表し;nは0または1を表し;Lは-C(=O)-N(R1)-等を表し;R1は水素原子またはC1-6アルキル基を表し;A2はフェニル基、C3-7シクロアルキル基等を表す。]で表される化合物もしくはそれらの薬学上許容される塩を有効成分とする神経変性疾患および精神疾患の治療薬。【選択図】なし
